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Liraglutide injection is indicated for adults with obesity or overweight who also have weight related medical problems, and pediatric patients (12-17 years) with a weight greater than 60 kg and obesity to help them lose weight and keep the weight off

The amount of added benefit or added side-effect burden is unknown without a direct trial

This 2-month discontinuation recommendation reflects semaglutide's pharmacokinetics rather than evidence of direct fertility impairment

Cognitive slowing manifests as word-finding difficulty or impaired attention and is typically dose-dependent, reversible upon dose reduction, and accentuated by co-administration of other sedatives