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Alzheimers Res Therapy
The drug interaction databases classify this as a moderate interaction, noting that "as you lose weight during treatment with phentermine, your dosage requirement of tirzepatide or any other diabetic medications may change." This is not a minor technicality
55 Apart from the weight reduction, GLP-1RAs have been shown to exert antihypertensive effects by promoting diuresis and having additional renal effects
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