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Cytokine activation has been noted in ME/CFS patients (225) and appears to increase along with disease severity (231)

For acute injuries like recent muscle strains or ligament sprains, 4 to 6 weeks of daily administration followed by 2 to 4 week breaks represents the consensus approach

SUPEROXIDE, HYDROGEN PEROXIDE, AND PEROXYNITRITE GENERATION Despite the fact that superoxide can be generated in extramitochondrial reactions, in most cell types mitochondria appear as the main source of superoxide generation

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