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However, recent reports suggest that GLP-1 drugs like Ozempic, Wegovy, and Mounjaro may exacerbate or accelerate the progression of DR, particularly in patients who experience a rapid improvement in blood glucose control after starting these medications
Many drugs can cross the luminal cell membrane but are then metabolized in the gut wall (typically by CYP3A4 e.g
Rodino-Klapac LR, Haidet AM, Kota J, Handy C, Kaspar BK, Mendell JR
Features fatty acid modification (acylation) for albumin binding and extended half-life
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