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Female participants in the study were more likely to have postdrome, and the most common symptoms were tiredness and a low-grade headache

This guidance also describes enrichment strategiestargeted inclusion of certain populations with the goal to more readily demonstrate a drug effectand recommends that even with enrichment, trials should keep their enrollment criteria as broad and representative as possible

The most notable ones include: Vitamin C : High concentrations can destabilise copper peptides, diminishing their regenerative effects