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[14] For N-acetylcysteine, studies have used doses between 600 mg and 1,800 mg daily, with 600 mg twice daily being a commonly studied regimen

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Orforglipron showed similar gastrointestinal side effects as other GLP-1 drugs, with the most common being diarrhea, nausea, indigestion, and constipation

So then there's other thing that's metabolized into is methanol