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By targeting multiple metabolic pathways, tirzepatide helps patients feel fuller longer, reduce cravings, and better manage calorie intake as part of a medically supervised weight loss plan

Its transdermal application is particularly beneficial for patients who may have difficulties with oral administration or for those seeking targeted treatment

While UK healthcare professionals can, in exceptional circumstances, prescribe unlicensed medicines under the MHRA 'specials' framework, this would rarely be appropriate for ED given the availability of licensed, evidence-based alternatives

And the evidence base that will land in front of the committee is, on most of these compounds, thin