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Adipose tissue plays a role in hormone metabolism, and substantial changes in body composition may temporarily affect hormonal balance

SCFAs exert anti-inflammatory properties through the suppression of pro-inflammatory mediators, including cytokines (TNF-, IL-6, and IL-1) as well as chemokines such as C-C motif ligand 2 (CCL2), C-C motif ligand 8 (CCL8), C-X-C motif ligand 5 (CXCL5), C-X-C motif ligand 8 (CXCL8), and C-X-C motif ligand 10 (CXCL10)