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Intravenous Safety Study (2025) Study design : Pilot safety/pharmacokinetic study Participants : 2 healthy adults (one 58-year-old male, one 68-year-old female) Intervention : Day 1: 10mg IV infusion over 1 hour
It takes part in the reduction of tocopheroloxyl radical (TocO) to -tocopherol with the appearance of an ascorbate radical (semidehydroascorbate): + + The ascorbate radical (A), in turn, is reduced to ascorbate (AN) with the help of reduced glutathione and the enzyme glutaredoxin: + 2GSH AH- + CSSG + + , as well as NADH-dependent semidihydroascorbine reductase: + NADH AH- + D+, and NADPH-dependent thioredoxin-reductase: + NADP AH- + NADP+ Reduced glutathione
Human Biology and Health
Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others References Thanan, R., Oikawa, S., Hiraku, Y., Ohnishi, S., Ma, N., Pinlaor, S., et al
