1, 2 IGF-1R is primarily activated by its high-affinity ligands, IGF-1 and IGF-2, though it can also bind insulin with lower affinity
Collaborative care models enhance lifestyle interventions by focusing on diet, exercise, and foot care, essential for preventing complications such as diabetic foot ulcers
Cholinergic hypothesis states that the degeneration of basal forebrain neurons in AD patients leads to dysfunction and death of cholinergic neurons in the forebrain, followed by extensive presynaptic denervation occurs, and the loss of specific subtypes of acetylcholine receptors, leading to cognitive decline in AD patients (39)
10.1001/jamainternmed.2024.4369 Summary Keywords cardiovascular disease, cardiovascular outcome, glucagon-like peptide-1 receptor agonists, heart failure, obesity Citation Turkistani Y (2025) Glucagon-like peptide-1 receptor agonists: a review from a cardiovascular perspective