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Only minimal amounts pass into breast milk, and it is considered safe for nursing infants
The first signs of B12 deficiency include persistent fatigue, weakness, lightheadedness, pale skin, tingling or numbness in the hands and feet, difficulty concentrating, and mood changes like irritability or mild depression
Tmax ~24-72 hours Half-Life: ~155 hours (6.5 days), enabling once-weekly dosing [2] Steady State: Achieved after approximately 4-5 weeks of weekly dosing Clearance: Primarily peptide degradation
It follows that control of PER1 expression may potentially be employed to reduce tumor growth
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