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Dosing: individualized, titrated to fasting glucose patterns
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Dementia and Alzheimers disease appear to arise from a chronic brain energy crisis, driven by impaired glucose utilization, insulin resistance, mitochondrial dysfunction, vascular insufficiency, and sustained neuroinflammation
Statement of ethics The study was approved by the West Midlands - Solihull Research Ethics Committee (17/WM/0179) and all subjects provided written informed consent according to the Declaration of Helsinki principles
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