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As with other drugs in the incretin-based therapy class, the most commonly reported side effects of retatrutide in clinical trials have been gastrointestinal in nature

Time-restricted eating limiting food intake to an eight-hour window or less and other forms of intermittent fasting may: Reduce insulin resistance Encourage fat loss Improve body composition when combined with strength training Learn more about intermittent fasting

When sustained, this degree of weight loss can provide meaningful improvements in metabolism and lipid management [11]