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GLP-1 receptor agonists are increasingly used to manage type 2 diabetes and support weight management in the UK

This suggests taurine might naturally help to regulate excitability in the thalamus, a key brain area

The pervasive challenge of adaptive resistance to ICIs and ICT Despite the unprecedented durability of responses achievable with cancer immunotherapy, the majority of patients exhibit either primary resistance (no initial response) or adaptive resistance (relapse after initial benefit) [78]

Baseline (before starting GLP-1 or supplements): 25-hydroxyvitamin D (target: 30-50 ng/mL) Vitamin B12 (target: above 400 pg/mL) Serum iron, ferritin, and TIBC Serum magnesium Serum zinc Complete metabolic panel CBC (to check for anemia) Follow-up testing at 3 and 6 months: Repeat all baseline labs Add: body composition measurement (DEXA scan is gold standard) to track lean mass vs fat mass changes Assess supplement adherence and adjust doses based on results The cost of basic nutritional bloodwork is minimal compared to the cost of undiagnosed deficiencies