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Additionally, EAAT2 is subject to caspase-3-mediated cleavage, generating toxic C-terminal fragments, the appearance of which precedes the manifestations of ALS neurodegeneration [386]

Monotreme GLP-1 peptides bind with lower affinity to the GLP-1 receptor than human GLP-1 We then asked how changes in pGLP-1 and eGLP-1 affect binding and activation of the GLP-1 receptor (GLP-1R)

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doi: 10.3389/fimmu.2020.620339 83 RussellSNDemetriouCValenzanoGEvansAGoSStanlyTet al