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Semaglutide slows gastric emptying, which can affect absorption timing of oral medications including certain thyroid medications and oral contraceptives

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PPARgamma agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation

The research is strongest in soft-tissue repair and gastrointestinal protection models, with evidence showing benefit in tendon healing, ligament repair, muscle injury, wound healing, angiogenesis, inflammatory modulation, and gut mucosal protection