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There is no official contraindication to taking NAD+ supplements alongside tirzepatide, and no formal drug-drug interaction has been documented in the medical literature or FDA labeling
Reports of GLP-1 RA regulation of thirst in animals is of interest, but the clinical relevance is not yet obvious
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Front Physiol 12:785879 Martens P, Mathieu C, Vanassche T (2023) The use of glucagon-like-peptide-1 receptor agonist in the cardiology practice
& Khrle, J
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