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In humans, calcitonin secretion operates independently of GLP-1 receptor stimulation

This dual action makes Bimagrumab unique compared to other weight loss medications that primarily focus on reducing appetite or increasing energy expenditure

Following the announcement at the beginning of 2023 that Pfizer would terminate the clinical development of another small molecule agonist, Lotiglipron (PF-07081532), the company's suspension of the Phase 3 clinical trial plan for Danuglipron this time has further exacerbated the situation for the company in the type 2 diabetes and obesity market represented by GLP-1R agonists

If you notice any other effects, check with your healthcare professional