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Upregulates BDNF in the prefrontal cortex
GLP-1 provides powerful appetite suppression and gastric slowing
The closest analogs are studies combining berberine with metformin, berberine with other GLP-1 receptor agonists in animal models, and mechanistic studies in cell culture
With semaglutide, this happens after about 4 to 5 weeks of consistent weekly dosing
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