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Hesperidin and naringin have both been found to inhibit ferroptosis by upregulating the Nrf2 pathway, offering protection to human myeloid cells (Tang et al., 2022
Most community protocols start cagrilintide at 0.25 mg/week once tirzepatide is established, then step up every 4 weeks to 0.5, 1.0, 1.7, and 2.4 mg/week
Histological endpoints were NASH resolution and no worsening of fibrosis (E1), improvement of fibrosis and no worsening of NASH (E2), and NASH resolution AND fibrosis improvement (E3)
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