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Systematic reviews show that more than 35 preclinical studies regularly produced positive histological and functional results, with no toxicity found in safety evaluations
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Environmental disruption of the circadian clock leads to altered sleep and immune responses in mouse
Additionally, the brain contains high levels of oxidizable lipids and metals, while possessing limited antioxidant mechanisms, which contributes to its heightened vulnerability to oxidative stress (Freitas, 2009)
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