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The endothelin receptor-B is required for the migration of neural crest-derived melanocyte and enteric neuron precursors
Other constituents, such as vinyl chloride, have a well-established association with hepatic angiosarcoma [28], whereas cadmium enhances liver cancer risk through proto-oncogene activation, oxidative stress induction, and stimulation of pro-inflammatory cytokines [29,30,31]
The above data imply that depletion of FXR1 promotes ferroptosis by down-regulating the expression of GPX4
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