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The drugs clinical trials reported nausea, vomiting, abdominal pain, diarrhea, and constipation most often as side effects
Its mechanism involves multiple pathways that contribute to weight loss: Appetite regulation : Semaglutide acts on receptors in the brain's appetite centres, particularly the hypothalamus, reducing hunger and increasing feelings of satiety Gastric emptying : It slows the rate at which food leaves the stomach, prolonging fullness after meals Glucose regulation : It enhances insulin secretion in a glucose-dependent manner and suppresses inappropriate glucagon release The slowed gastric emptying associated with Wegovy is a primary contributor to the nausea many patients experience, particularly during dose escalation
Based on a Wegovy clinical study in adults with obesity or overweight and weight-related medical problems, mean weight loss achieved at 2 years was 15.2% vs
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