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FDX1, as a key regulator of cuproptosis, efficiently reduces relatively stable Cu 2+ to the more cytotoxic Cu, ultimately inducing cuproptosis [12]

The transcriptional regulation of DNL is mainly orchestrated by two key transcription factors: sterol regulatory element-binding protein 1c (SREBP1c), which is activated by insulin and liver X receptor , and carbohydrate regulatory element-binding protein (ChREBP), which is activated by carbohydrates [41,42,43] (Fig

Instead of three large meals, eating four to six smaller meals with controlled fat content supports both medication efficacy and post-surgical digestive comfort

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