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Increase again if additional glycemic control is needed
The trial involved 1879 patients with inadequate glycemic control on metformin monotherapy, who were randomly assigned to receive tirzepatide at doses of 5 mg, 10 mg, or 15 mg, or semaglutide at a dose of 1 mg.After 40 weeks of treatment, all doses of tirzepatide were found to be noninferior and superior to semaglutide in terms of reducing glycated hemoglobin (HbA1c) levels
Earlier studies using these mice include (5-7, 101)
As featured in Microdose semaglutide delivers the same GLP-1 mechanism at a lower starting dose ideal for first-time patients who want to minimize side effects during ramp-up
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