Nausea (most common, typically dose-dependent and transient) Diarrhea or constipation during dose escalation Vomiting, especially when starting or increasing dose Reduced appetite and early satiety Injection site reactions (redness, bruising) Fatigue, particularly in early weeks Rare: Pancreatitis discontinue immediately with severe abdominal pain Rare: Thyroid C-cell effects (contraindicated with MEN2 or thyroid cancer history) AOD-9604 is a modified C-terminal fragment (residues 176191, Tyr-hGH177-191) of human growth hormone, studied for lipolytic and anti-obesity properties
Research in animal models has measured new blood vessel growth, how tendon cells move and spread, and how tissue repairs after injury
Problems such as SIBO, altered intestinal microbiota, and delayed gastric emptying have added to the difficulties of oral therapy in PD, often culminating in commonly observed motor fluctuations such as delayed on or early-morning off sometimes associated with severe non-motor symptoms as well
But, for testosterone replacement, lower doses are better to keep testicular function