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To better understand the reliability of the reviewed studies, we conducted a methodological quality assessment based on key design features, including randomization, blinding, use of control groups, and sample size

Kim KB, Kim YW, Lim SK, et al

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Thats because its incorporated into cell membranes in the top layer of skin (the epidermis), forming a protective web around skin cells, helping to stop moisture being lost and giving skin a healthy appearance