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Less common but more serious reported effects include pancreatitis, gallbladder disease, and potential thyroid C-cell tumours (observed in animal studies with semaglutide, though not confirmed in humans)
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CYP2E1 and ALDH enzymatic activity CYP2E1 activity was assessed by measuring the rate of oxidation of p -nitrophenol (PNP) to p -nitrocatechol as described 54
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