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According to Table 3 , a characteristic pro-inflammatory state can be observed in SZ patients, manifested by persistently elevated levels of pro-inflammatory cytokines such as IL-6, IL-1, and TNF- in both peripheral blood and CSF, accompanied by a relative deficiency of anti-inflammatory cytokines like IL-10 and TGF-

Specific allergic manifestations consisting of swelling of eyelids, lips, pharynx and larynx, urticaria, asthma, and bronchospasm, sometimes with a concomitant fall in blood pressure

Tirzepatide is contraindicated in specific patient populations, and careful risk-benefit assessment is required for others

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