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Before discontinuing use of a prescribed incretin receptor agonist, there are alternatives that may help maintain a more stable weight
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The programs cost may prove to be a limiting factor
Their primary mechanisms include: Enhancing insulin secretion from pancreatic beta cells in response to elevated blood glucose Suppressing glucagon release , thereby reducing hepatic glucose production Slowing gastric emptying , which prolongs satiety and reduces appetite Acting on appetite centres in the brain , particularly the hypothalamus, to reduce food intake [17] [18] These combined effects lead to improved glycaemic control in people with type 2 diabetes and significant weight reduction in those using these medications for obesity management
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