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Despite the dose discrepancy, the 1-month IGF-I can be seen to overlap between GHD and TS, likely reflecting differences in sensitivity to r-hGH, yet the polymorphisms associated with this change in serum IGF-I differ
Systemic distribution requires higher absolute doses than locally acting peptides like BPC-157
Preclinical results are consistently positive in tissue repair contexts, but animal data cannot confirm human efficacy
In animal models, this combination has been used to study damage amelioration in multiple sclerosis, peripheral axonal pathology, and brain ischemia
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