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When ibuprofen is necessary , several strategies can minimise risks: Take with food reduces direct gastric irritation, though Wegovy slows digestion Use the lowest effective dose typically 200-400mg for mild to moderate pain Limit duration avoid prolonged courses without medical supervision Stay well-hydrated particularly important given Wegovy's gastrointestinal effects Consider gastric protection proton pump inhibitors (PPIs) may be appropriate for extended NSAID use if recommended by a clinician based on your risk factors For over-the-counter use, ibuprofen should typically not exceed 1.2g per day (e.g., 400mg three times daily) unless advised by a healthcare professional
Even light activity boosts energy Make sure your iron and B12 levels are good (especially if you feel wiped) Fatigue Is Normal You are losing a significant amount of weight (especially quickly) And that alone can trigger fatigue
If your primary concern is insulin resistance and appetite control, tirzepatide might be the better choice
It also helps with weight loss by reducing appetite and slowing digestion
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