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Albiglutide in the Harmony Outcomes trial showed a 22% reduction in MACE in patients with established ASCVD (20), while exenatide (EXSCEL trial) (21) and lixisenatide (ELIXA trial) (22) did not meet superiority, though both demonstrated CV safety
And the loss of physical function is because of low muscle mass or chronic fractures from osteoporosis, which is preventable
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