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The most commonly reported adverse reactions in clinical trials were gastrointestinal: nausea (up to 18 to 24% of users), diarrhea (up to 17%), vomiting, constipation, decreased appetite, dyspepsia, and abdominal pain

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Without treating thyroid function, Semaglutide may only deliver partial results

Makary singled out the ad in last week's Journal of the American Medical Association, calling it a "brazen" example of how advertising is "contributing to America's culture of overreliance on pharmaceuticals for health." Hims and similar companies initially sold cheap generic versions of drugs for hair loss, erectile dysfunction and other health issues