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In Phase I, the drug undergoes oxidation and reduction reactions, primarily mediated by liver enzymes known as the cytochrome P450 enzyme system

It recognizes that immune imbalance, chronic inflammation, and metabolic dysfunction often stem from disruptions in the gut-immune-hormone axis

Next, after being exposed to 0, 100, 200, and 300 M H 2 O 2 for 24 h, a dose-dependent decrease in chondrocyte viability was observed, with significant decrease starting at 200 M H 2 O 2 (Fig