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IP3 might then prompt the release of calcium ions (Ca2+) from intracellular reserves, whereas DAG potentially activates protein kinase C (PKC)
Regulating Satiety Pathways: In the hypothalamus, GLP-1 RAs stimulate neurons that promote satiety (POMC/CART neurons) and inhibit neurons that drive hunger (NPY/AgRP neurons), reducing food intake and enhancing fullness (Zheng et al., 2024)
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