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For instance, both diabetic and non-diabetic women with insulin resistance have higher risk to develop breast, endometrial and ovarian cancer, and results from studies in ovarian and cervical cancer suggest that the first-line type 2 diabetes drug and anti-insulin resistance agent metformin is a good candidate in combination therapies for these cancers (4, 9)

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As one of the first compounds specifically identified to inhibit ferroptosis, Fer-1 effectively prevents cell death in multiple in vitro models and reduces tissue injury in animal studies (413)