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Additionally, several medicinal plants have demonstrated renal benefits in human clinical trials, including Rheum officinale (available in capsule, pill, and powder forms), Cordyceps sinensis (capsule), Glycyrrhiza glabra (supplement), curcumin (capsule), Lespedeza capitata (tincture), and Parietaria judaica (tonic)

90,91 GLP-1R signaling is suggested to intersect with sirtuin-mediated processes to promote mitochondrial biogenesis and mitophagy, thereby supporting cellular energy homeostasis and mitigating oxidative stress in aging tissues, with evidence primarily from cellular and rodent models

4ak used a within-individual paired design

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