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Their mechanisms of action (stimulating insulin, curbing appetite, slowing gastric emptying) translate into meaningful clinical benefits, supported by robust evidence from trials and reflected in guideline recommendations by ADA/EASD and others

We administered 75 mg/kg caffeine and 100 mg/kg EGCG to observe the commonality and specificity of the two treatments in an HFHC-induced mouse model of NASH

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Whilst these medications do not selectively 'burn' belly fat through direct mechanisms, clinical evidence demonstrates they promote significant overall weight loss, including reductions in visceral adipose tissuethe metabolically harmful fat surrounding internal organs