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Furthermore, it has been demonstrated that complete truncal vagotomy may be associated with a reduced risk of PD development compared to highly selective vagotomy or control conditions [122, 123]
Lipid-induced TLR-4 expression and subsequent secretion of tumor necrosis factor- activate the NF-kb signaling pathway, resulting in the release of pro-inflammatory factors and promoting the proliferation and steroidogenic activities, which in turn stimulate excess ovarian androgen production
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