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A patient with unexplained fatigue should be worked up, not injected masking a B12 deficiency of unclear cause, or an unexamined thyroid problem, with a monthly shot is a real clinical risk
doi:10.1507/endocrj.52.571
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NICE Clinical Knowledge Summaries and British Society for Haematology guidelines support B12 supplementation in these clinical contexts, with treatment regimens tailored to the underlying cause
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