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The 200%+ GLP-1 increase figure comes from the average of both studies combined
The reasons are multifactorial: chronic inflammation damages blood vessel walls, corticosteroid use raises cholesterol and blood pressure, lupus-specific antibodies (particularly antiphospholipid antibodies) increase clotting risk, and the metabolic disruption caused by both the disease and its treatments creates a perfect storm for atherosclerosis
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Regarding causality, Zhou et al
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