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Early doses are often used to help the body adjust, so they may not produce the same effect as later therapeutic doses
The longer it goes on, the more likely you are to develop symptoms
[114] This functionality is lost in vitamin B 12 deficiency, and can be measured clinically as an increased serum methylmalonic acid (MMA) concentration
Importantly, phentermine and phentermine-topiramate extended-release (Qsymia) are contraindicated in hyperthyroidism and should be avoided in patients with active Graves disease, as they may worsen tachycardia and other sympathomimetic effects
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