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Landmark trials such as SUSTAIN and STEP demonstrated significant reductions in HbA1c levels and body weight in T2DM and obesity (4, 5)
Acknowledgements and funding The authors work on gut-derived hormones and obesity-diabetes has been generously supported over many years by Diabetes UK, Invest Northern Ireland, the Irish Endocrine Society, Northern Ireland Department for the Economy, and Ulster University Strategic Funding
In some ways, were trying to solve the evidence-translation gap. Once a drug or therapy has been demonstrated safe and effective in clinical trials, its no secret that it takes a long time to be adopted into mainstream practice, he said
doi:10.1016/0009-9236(95)90040-3
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