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Retatrutide was found to inhibit the HBP, thereby preventing YAP O-GlcNAcylation and promoting its degradation

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Treatment failure in around 10% of about 300 patients was associated with large cysts / pseudocysts, non-compliance in unreformed alcoholics, undiagnosed neoplasia in two (adenocarcinoma, papillary mucinous) and in the described patients with recurrent acute pancreatitis (JM Braganza, unpublished)