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ATP depletion stimulates PKC-alpha activity and leads to translocation of the enzyme to the plasma membrane, thereby enhancing serine phosphorylation of membrane proteins, such as the Ca 2+ -permeable cation channel (Fig
J Small Anim Pract 65(3):153175 Pei J, Pan X, Wei G, Hua Y (2023) Research progress of glutathione peroxidase family (GPX) in redoxidation
An open-label study (n=42) found that IV NAC (50 mg/kg) combined with oral NAC (500 mg twice daily) for 3 months increased brain glutathione levels (measured by MRS), increased dopamine transporter binding (measured by DaTscan), and improved UPDRS motor scores (Monti et al., PLoS One, 2016) [53]
Oxidative Medicine and Cellular Longevity, 2017 , 8416763
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