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In addition, unlike studies in human volunteers, which have historically comprised the majority of fMRI research [62] the specific mechanisms that alter functional connectivity in GLP-1R KO mice versus WT mice can be investigated with the full toolset available to rodent neuroscience
Studies with the monoclonal antibody bimagrumab in combination with incretin mimetics like semaglutide or tirzepatide are ongoing to assess the affect on lean muscle mass preservation
PMC3359723 Pickart, L., et al
Goldenring, R.S
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