glutathione lysosome Lysosomes as dynamic regulators of cell and organismal homeostasis Lysosomal cyst(e)ine storage potentiates tolerance

Table 2 shows completed and ongoing ADC clinical trials for prostate cancer, grouped by their molecular targets

Disease progression on 177Lu-PSMA-617 is inevitable even in patients who are strongly PSMA-positive on imaging, with patients either having no response or progressing long-term despite having an excellent initial response 258

Tacrine and ganciclovir alter mtDNA homeostasis from different mechanisms, including inhibition of mtDNA replication and translation, to induce mitochondrial damage [132, 142]

Uneven or patchy skin tone : Irregular melanin activity creates dark patches that require targeted treatment