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1- Role in Macrophage Metabolism Synthesis of Nucleotides and Amino Acids The PPP is also integral to the synthesis of nucleotides and amino acids in macrophages

Wu et al., 2020), illustrative of the complexity of the processes involved

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Most of the GSH (8085%) is stored in the cytosol, 1015% in the mitochondria (with an equal concentration between matrix and cytosol, thus requiring specific transport systems) and a small part in the endoplasmic reticulum (ER) ( 2.1