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It should be noted that fibrotic regulation is a multi-layered process involving post-transcriptional control, extracellular matrix deposition, and tissue architecture, which are not fully captured by transcriptomic analyses alone
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Guided by nature, which uses an NADP + -producing glutathione reductase system to maintain a reducing environment within cells, researchers have now developed a similar system for regenerating NADP + from NADPH
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